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Santa Cruz Biotechnology, Inc.
SANTA CRUZ
HNF-1 (H-205): sc-8986
BIOTECHNOLOGY
BACKGROUND HNF-1 (α and β), HNF-3 (α, β and γ), HNF-4 (α and γ), and HNF-6 compose, in part, a homoeprotein family designated the Hepatocyte Nuclear Factor family (1-4). The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus (1). HNF-3α, HNF-3β and HNF-3γ regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3α and HNF-3β have also been shown to be involved in gastrulation events such as body axis formation (2,4). HNF-4 α and HNF-4 γ have been shown to be important for early embryo development.
SC-8986 Datasheet