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SC-7415 - Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors

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Part number SC-7415
Manufacturer Unknown Manufacturer
File Size 140.11 KB
Description Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors
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Santa Cruz Biotechnology, Inc. SANTA CRUZ G α 16 (C-18): sc-7415 BIOTECHNOLOGY BACKGROUND Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein a, b and g polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors.
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